A database of hormones and their receptors |
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HMRbase accession number | 10743 |
Swiss-prot Accession number | P20391 (Sequence in FASTA format) |
Description | Somatotropin (Growth hormone). |
Source organism | Katsuwonus pelamis (Skipjack tuna) (Bonito) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Scombroidei;Scombridae; Katsuwonus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the somatotropin/prolactin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation |
Protein Length | 185 Amino acids |
Molecular weight | 21235 |
References | 1 PubMed abstract 3246482 |
Domain Name | Hormone_1 |
Hormone Name | Somatotropin |
Mature Hormone Sequence | QPITESQRLFSIAVSRVQNLHLLAQRLFSDFESSLQTQEQRQLNKIFLQDFCNSDYIISPIDKHETQRSSVLKLLSISYRLVESWEFPSRSLSGAQRNQISEKLSDLKMGIQLLIRANQDGAEMFADSSALQLAPYGNYYQSLGGDESLRRNYELLACFKKDMHKVETYLMVAKCRLSPEANCTL |
Position of mature hormone in Pre-Hormone protein | 185 Residues from position (1-185) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10846 |
Swiss-prot Accession number | P01340 (Sequence in FASTA format) |
Description | Insulin [Contains: Insulin B chain; Insulin A chain]. |
Source organism | Katsuwonus pelamis (Skipjack tuna) (Bonito) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Scombroidei;Scombridae; Katsuwonus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the insulin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver |
Protein Length | 50 Amino acids |
Molecular weight | 5698 |
References | 1 PubMed abstract 14035061 2 PubMed abstract 14036898 |
Domain Name | Insulin |
Hormone Name | Insulin B chain |
Mature Hormone Sequence | AANPHLCGSHLVEALYLVCGERGFFYQPK |
Position of mature hormone in Pre-Hormone protein | 29 Residues from position (1-29) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | 2G56 |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10847 |
Swiss-prot Accession number | P01340 (Sequence in FASTA format) |
Description | Insulin [Contains: Insulin B chain; Insulin A chain]. |
Source organism | Katsuwonus pelamis (Skipjack tuna) (Bonito) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Scombroidei;Scombridae; Katsuwonus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the insulin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver |
Protein Length | 50 Amino acids |
Molecular weight | 5698 |
References | 1 PubMed abstract 14035061 2 PubMed abstract 14036898 |
Domain Name | Insulin |
Hormone Name | Insulin A chain |
Mature Hormone Sequence | GIHZZCCHKPCBIFZLZBYCN |
Position of mature hormone in Pre-Hormone protein | 21 Residues from position (30-50) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | 2G56 |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |